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Türkiye Vaccine Institute

Phase IV

Large-scale volunteer participation, investigation of rare adverse effects, and safety monitoring

  • Clinical trials conducted after a vaccine has received official regulatory approval are classified as Phase IV studies.
  • This phase encompasses research aimed at detecting extremely rare adverse effects. Furthermore, it includes studies designed to evaluate vaccine response across diverse participant groups with underlying health conditions.
  • These studies are typically conducted with thousands of volunteers and may span several years.